Biomarkers · Coagulation

Soluble ICAM-1 (sICAM-1)

Lower values go with lower risk of death. Not measured in our NHANES panel. The curve is drawn from the published study (source below).

sICAM-1 and risk of death

Published curve higher than the NHANES fitNHANES fit higher

Risk of death relative to the curve's reference value, drawn from the published study (source below).

Published risk of death1.30×per 1 SD increase in sICAM-1 (89.7 ng/mL), men (95% CI 1.10–1.40) · Cardiovascular Health Study, adults aged >=65 free of clinical CVD at baseline; case groups plus 643 event-free subjects

sICAM-1 by age and sex

Each bar runs from the 5th to the 95th percentile, the darker part from the 25th to the 75th, and the tick is the median. Not a reference range or a target.

The percentiles as a table

Each row is one sex and age band: the values below which 5%, 25%, 50%, 75% and 95% of people fall (ng/mL), from the survey named in the row. Not a reference range or a target.
Sex	Age	5th	25th	Median	75th	95th	n	Cycle / source
All	40-59	135	176	214	260	398	347	MIDUS 3 Biomarker Proj…
All	60+	134	181	218	271	374	388	MIDUS 3 Biomarker Proj…
All	all	134	179	215	266	386	735	MIDUS 3 Biomarker Proj…
Men	40-59	143	174	207	244	337	132	MIDUS 3 Biomarker Proj…
Men	60+	138	177	216	270	380	193	MIDUS 3 Biomarker Proj…
Men	all	139	175	213	262	365	325	MIDUS 3 Biomarker Proj…
Women	40-59	123	180	219	264	430	215	MIDUS 3 Biomarker Proj…
Women	60+	127	185	219	274	372	195	MIDUS 3 Biomarker Proj…
Women	all	125	181	219	267	401	410	MIDUS 3 Biomarker Proj…

Sources

Risk curve: Jenny 2006 (PMID 16409459): all-cause HR 1.3 (1.1-1.4) per 1 SD increase in sICAM-1 (89.7 ng/mL), men; women HR 1.2 (1.1-1.3). Scaled to US values (NHANES).
Jenny et al. Soluble intracellular adhesion molecule-1 is associated with cardiovascular disease risk and mortality in older adults. Journal of thrombosis and haemostasis : JTH. 2006;4:107-13.

Map Soluble ICAM-1 (sICAM-1) against another biomarker.

Map sICAM-1 against another marker