Biomarkers · Coagulation
Plasma Viscosity
Lower values go with lower risk of death. Not measured in our NHANES panel. The curve is drawn from the published study (source below).
Plasma Viscosity and risk of death
Published curve higher than the NHANES fitNHANES fit higher
Risk of death relative to the curve's reference value, drawn from the published study (source below).
What studies found when this marker was changed
They describe what happened in those study groups, not a recommendation. See all catalogued interventions.
Measured changes in Plasma Viscosity, study by study
3 effects with a numeric size, each from one study arm: the dot is the reported change, the line its 95% interval where one was given. Green points move the marker the way lower risk of death lies; amber the other way. Study results in the groups studied, not predictions for a person.
| Type | Intervention | Reported effect | Evidence | Source |
|---|---|---|---|---|
| clinical | Intensified glycaemic management with diet, exercise and insulin for ~14 weeks in type 2 diabetes | Plasma viscosity decreased 3% after 14 +/- 3 weeks of intensified management | non-randomised trial | Chong-Martinez B, Buchanan TA, Wenby RB, Meiselman HJ. Diabet Med. 2003. |
| pharmacologic | Oral calcium dobesilate in diabetic retinopathy | Plasma viscosity -0.36 cP (95% CI -0.63 to -0.09) | meta-analysis | Zhang X, Liu W, Wu S, et al. Sci China Life Sci. 2015. |
| supplement | Omega-3 fatty acid (fish oil) supplementation in people with intermittent claudication | Plasma viscosity +0.03 mPa.s (95% CI -0.02 to 0.08), no significant effect | meta-analysis | Campbell A, Price J, Hiatt WR. Cochrane Database Syst Rev. 2013. |
Sources
- Risk curve: Lowe 2024 (PMID 36828622): all-cause HR 1.21 (1.17-1.25) per 1 SD increase in plasma viscosity. Scaled to published population values.
- Lowe et al. Plasma viscosity, immunoglobulins and risk of cardiovascular disease and mortality: new data and meta-analyses. Journal of clinical pathology. 2024;77:394-401.
Map Plasma Viscosity against another biomarker.
Related markers: Angiopoietin-2 · Coagulation Factor VIII · Coagulation Factor VIIc · D-dimer · Plasminogen Activator Inhibitor-1 (PAI-1) · Soluble ICAM-1 (sICAM-1) · von Willebrand Factor (vWF)