PFLPhysiological Fitness Landscape

Biomarkers · Coagulation

Coagulation Factor VIII

Lower values go with lower risk of death. Not measured in our NHANES panel. The curve is drawn from the published study (source below).

Coagulation Factor VIII and risk of death

Published curve higher than the NHANES fitNHANES fit higher

Risk of death relative to the curve's reference value, drawn from the published study (source below).

Published risk of death1.63×top third vs bottom third of factor VIII, fully risk-factor adjusted (95% CI 1.35–1.96) · Glasgow MONICA: men and women aged 30-74 without baseline CVD (382 to 1,123 per assay), followed 15-20 years