Biomarkers · Bone & Mineral

Osteoprotegerin (OPG)

Lower values go with lower risk of death. No risk curve catalogued yet.

Published risk of death1.40×per SD (0.11 ng/mL) increase in serum OPG, age-adjusted (95% CI 1.20–1.80) · 490 white women aged >=65 y from a prospective cohort (Study of Osteoporotic Fractures sample)

What else moves this marker

They describe those study groups, not an individual, and an association is not a cause.

Diseases and conditions

Each row is one study: what it compared and the change it reported in this marker.
What	Effect on the marker	Comparison · population	Source
↑ Charcot neuroarthropathy · serum OPG in diabetics with Charcot neuroarthropathy vs healthy controls	SMD +1.043 (95% CI 0.676 to 1.409)	Charcot neuroarthropathy vs healthy controls · 7 publications (12 studies)	meta analysis · PMID 33394132

Sources

Browner et al. Associations of serum osteoprotegerin levels with diabetes, stroke, bone density, fractures, and mortality in elderly women. The Journal of clinical endocrinology and metabolism. 2001;86:631-7.