Thyroxine (Total T4)

No risk curve catalogued yet.

Total T4 by age and sex

Each bar runs from the 5th to the 95th percentile, the darker part from the 25th to the 75th, and the tick is the median. Not a reference range or a target.

The percentiles as a table

Each row is one sex and age band: the values below which 5%, 25%, 50%, 75% and 95% of people fall (ug/dL), from the survey named in the row. Not a reference range or a target.
Sex	Age	5th	25th	Median	75th	95th	n	Cycle / source
All	20-39	5.72	6.80	7.65	8.50	10.7	570	NHANES 2011-2012
All	40-59	5.50	6.85	7.78	8.75	10.8	507	NHANES 2011-2012
All	60+	5.72	7.27	8.11	9.22	11.2	512	NHANES 2011-2012
All	all	5.65	6.92	7.84	8.80	10.9	1,589	NHANES 2011-2012
Men	20-39	5.42	6.59	7.55	8.37	10.3	295	NHANES 2011-2012
Men	40-59	5.52	6.51	7.47	8.52	10.3	251	NHANES 2011-2012
Men	60+	5.59	6.93	7.92	8.92	11.2	260	NHANES 2011-2012
Men	all	5.53	6.60	7.55	8.54	10.5	806	NHANES 2011-2012
Women	20-39	5.85	7.11	7.83	8.86	11.2	275	NHANES 2011-2012
Women	40-59	5.14	7.11	8.00	8.90	10.9	256	NHANES 2011-2012
Women	60+	6.10	7.66	8.27	9.41	11.1	252	NHANES 2011-2012
Women	all	5.83	7.22	8.06	8.99	11.1	783	NHANES 2011-2012

What studies found when this marker was changed

They describe what happened in those study groups, not a recommendation. See all catalogued interventions.

Measured changes in Total T4, study by study

1 effect with a numeric size, each from one study arm: the dot is the reported change, the line its 95% interval where one was given. Study results in the groups studied, not predictions for a person.

Each row is one study: what was changed, the effect it reported on this marker, and the source.
Type	Intervention	Reported effect	Evidence	Source
pharmacologic	Oral conjugated equine estrogens 0.625 mg daily for 12 weeks in naturally menopausal women (randomised crossover vs transdermal estradiol)	Total T4 rose by a mean +28.4% (SD 29.2%) from baseline after 12 weeks of oral CEE; n=25 completers	RCT	Shifren JL, et al. Menopause. 2007;14(6):985-994.

Sources

See the catalogue entry in the research dashboard.