Biomarkers · Endocrine

Estradiol (17beta-Estradiol)

Lower values go with lower risk of death. Not measured in our NHANES panel. The curve is drawn from the published study (source below).

Estradiol (17beta-Estradiol) and risk of death

Published curve higher than the NHANES fitNHANES fit higher

Risk of death relative to the curve's reference value, drawn from the published study (source below).

Published risk of death1.23×increased quartiles of estradiol (highest vs lowest quartile, men) (95% CI 1.06–1.43) · Danish men aged 30-70 from general-population surveys MONICA I-III and Inter99 (1982-2001), followed to 2012 (up to 30 y); men only

Estradiol (17beta-Estradiol) by age and sex

Each bar runs from the 5th to the 95th percentile, the darker part from the 25th to the 75th, and the tick is the median. Not a reference range or a target.

The percentiles as a table

Each row is one sex and age band: the values below which 5%, 25%, 50%, 75% and 95% of people fall (pg/mL), from the survey named in the row. Not a reference range or a target.
Sex	Age	5th	25th	Median	75th	95th	n	Cycle / source
All	20-39	9.02	20.6	30.2	67.4	208	1,670	NHANES 2015-2016
All	40-59	2.11	13.0	22.8	35.8	156	1,693	NHANES 2015-2016
All	60+	2.11	4.85	12.9	23.9	40.2	1,688	NHANES 2015-2016
All	all	2.11	12.0	23.0	36.5	155	5,051	NHANES 2015-2016
Men	20-39	12.0	18.6	23.9	29.7	42.2	823	NHANES 2015-2016
Men	40-59	12.9	18.1	23.5	29.0	41.1	795	NHANES 2015-2016
Men	60+	13.0	18.8	24.0	30.4	47.2	844	NHANES 2015-2016
Men	all	12.6	18.4	23.8	29.8	42.0	2,462	NHANES 2015-2016
Women	20-39	4.24	32.5	68.2	133	286	847	NHANES 2015-2016
Women	40-59	2.11	5.76	18.5	77.3	220	898	NHANES 2015-2016
Women	60+	2.11	2.11	5.52	8.75	20.3	844	NHANES 2015-2016
Women	all	2.11	5.37	17.2	76.0	215	2,589	NHANES 2015-2016

Sources

Risk curve: Holmboe 2015 (PMID 26488309): all-cause HR 1.23 (1.06-1.43) increased quartiles of estradiol (highest vs lowest quartile, men). Scaled to US values (NHANES).
Holmboe et al. The Association of Reproductive Hormone Levels and All-Cause, Cancer, and Cardiovascular Disease Mortality in Men. The Journal of clinical endocrinology and metabolism. 2015;100:4472-80.

Map Estradiol (17beta-Estradiol) against another biomarker.

Map Estradiol (17beta-Estradiol) against another marker