FSH by age and sex
Each bar runs from the 5th to the 95th percentile, the darker part from the 25th to the 75th, and the tick is the median. Not a reference range or a target.
The percentiles as a table
| Sex | Age | 5th | 25th | Median | 75th | 95th | n | Cycle / source |
|---|---|---|---|---|---|---|---|---|
| Women | 35-39 | 1.94 | 3.97 | 5.82 | 7.62 | 24.7 | 353 | NHANES 1999-2002 |
| Women | 40-59 | 3.21 | 6.90 | 20.2 | 56.8 | 92.6 | 1,283 | NHANES 1999-2002 |
| Women | 60 | 17.8 | 35.6 | 54.4 | 79.0 | 99.5 | 75 | NHANES 1999-2002 |
| Women | all | 2.59 | 5.69 | 12.4 | 50.3 | 89.4 | 1,711 | NHANES 1999-2002 |
What studies found when this marker was changed
They describe what happened in those study groups, not a recommendation. See all catalogued interventions.
Measured changes in FSH, study by study
3 effects with a numeric size, each from one study arm: the dot is the reported change, the line its 95% interval where one was given. Study results in the groups studied, not predictions for a person.
| Type | Intervention | Reported effect | Evidence | Source |
|---|---|---|---|---|
| nutraceutical | Soy isoflavones, median 75 mg/day for a median of 24 weeks, in postmenopausal women (40 RCTs) | No effect on FSH: MD -0.02 IU/L (95% CI -2.39 to 2.35) | meta-analysis | Viscardi G, et al. Adv Nutr. 2025. Effect of Soy Isoflavones on Measures of… |
| nutraceutical | Combined black cohosh, soy isoflavone and flaxseed SDG lignan supplement daily for 90 days in postmenopausal women | FSH -6.7% difference vs placebo at 90 days (estradiol +12.6%) | RCT | Pokushalov E, et al. Eur J Nutr. 2025. Assessing the combined effects of Black… |
| pharmacologic | Neurokinin 3 receptor antagonist fezolinetant 180 mg/day for 12 weeks in women with PCOS | Adjusted mean FSH change -1.46 IU/L (SE 0.32) vs -0.57 IU/L with placebo at 12 weeks (P = .03) | RCT | Fraser GL, et al. J Clin Endocrinol Metab. 2021. Randomized Controlled Trial of… |
Sources
- See the catalogue entry in the research dashboard.
Related markers: Estradiol (17beta-Estradiol) · Growth Hormone (GH) · Prolactin · Serum Leptin · Thyroxine (Total T4)