Biomarkers · Inflammation
Stromal Cell-Derived Factor-1 (SDF-1/CXCL12)
Lower values go with lower risk of death. No risk curve catalogued yet.
Published risk of death2.50×third tertile of plasma SDF-1 (reference category not reported) (95% CI 1.20–5.20) · 254 patients with acute coronary syndrome, long-term follow-up
What studies found when this marker was changed
They describe what happened in those study groups, not a recommendation. See all catalogued interventions.
Measured changes in SDF-1/CXCL12, study by study
1 effect with a numeric size, each from one study arm: the dot is the reported change, the line its 95% interval where one was given. Green points move the marker the way lower risk of death lies; amber the other way. Study results in the groups studied, not predictions for a person.
| Type | Intervention | Reported effect | Evidence | Source |
|---|---|---|---|---|
| exercise | Two weeks (six sessions) of high-intensity versus low-intensity stationary cycling in adult cancer survivors (randomised crossover) | Plasma CXCL12 (SDF-1) was 150.3 pg/mL (SEM 51.8) lower after 2 weeks of high- than low-intensity training (0.1503 ng/mL); crossover, n=20 | RCT | Clifford BK, et al. Eur J Clin Invest. 2023;53(7):e13984. |