Biomarkers · Inflammation

Alpha-1-Antichymotrypsin (AACT)

Lower values go with lower risk of death. No risk curve catalogued yet.

Published risk of death1.21×per SD plasma alpha1-antichymotrypsin (men) (95% CI 1.11–1.33) · Men in the British National Diet and Nutrition Survey of People Aged 65+ (community-living subset; total cohort 1,054)

What studies found when this marker was changed

They describe what happened in those study groups, not a recommendation. See all catalogued interventions.

Measured changes in AACT, study by study

1 effect with a numeric size, each from one study arm: the dot is the reported change, the line its 95% interval where one was given. Green points move the marker the way lower risk of death lies; amber the other way. Study results in the groups studied, not predictions for a person.

Each row is one study: what was changed, the effect it reported on this marker, and the source.
Type	Intervention	Reported effect	Evidence	Source
supplement	Daily multi-nutrient supplement (branched-chain amino acids, taurine, anti-inflammatory plant extracts, B vitamins) for 28 days	Alpha-1-antichymotrypsin fell from 108.9 to 55.5 ug/mL in men after 28 days	RCT	Dunn-Lewis C, Kraemer WJ, Kupchak BR, et al. Nutr J. 2011.

Sources

Bates CJ, Hamer M, Mishra GD. A study of relationships between bone-related vitamins and minerals, related risk markers, and subsequent mortality in older British people: the National Diet and Nutrition Survey of People Aged 65 Years and Over. Osteoporos Int. 2012;23(2):457-466.