PFLPhysiological Fitness Landscape

Biomarkers · Hematology

Reticulocyte Percentage

No risk curve catalogued yet.

What studies found when this marker was changed

They describe what happened in those study groups, not a recommendation. See all catalogued interventions.

Measured changes in Reticulocyte Percentage, study by study

3 effects with a numeric size, each from one study arm: the dot is the reported change, the line its 95% interval where one was given. Study results in the groups studied, not predictions for a person.

Each row is one study: what was changed, the effect it reported on this marker, and the source.
TypeInterventionReported effectEvidenceSource
clinicalTotal splenectomy (vs partial) in children with hereditary spherocytosis; change at 1 yearReticulocytes reduced by 12.5 percentage points after total splenectomy vs 6.5 after partial splenectomy at 1 year; hemoglobin +3.6 vs +2.2 g/dLmeta-analysisGuizzetti L. Pediatr Blood Cancer. 2016. Total versus partial splenectomy in…
clinicalTotal or partial splenectomy in sickle cell disease patients (18 studies, 756 patients)Both total and partial splenectomy decreased reticulocytes by 2% (0.8-3.2%); hemoglobin unchangedmeta-analysisRoshdy MR, et al. J Pediatr Surg. 2025. Partial Splenectomy Versus Total…
supplementVitamin E supplementation in patients with glucose-6-phosphate dehydrogenase deficiency (6 studies)Reticulocytes -1.42% vs control in acute hemolysis (-1.39 in chronic hemolysis; -1.41% in before/after studies); hemoglobin +1.18 to +2.72 g/dLmeta-analysisAbdelwahab OA, et al. Medicine (Baltimore). 2023. The potential role of vitamin…