Biomarkers · Oxidative Stress

Peroxiredoxin-4 (PRDX4)

Lower values go with lower risk of death. No risk curve catalogued yet.

Published risk of death1.17×per doubling of Prx4 levels (95% CI 1.06–1.29) · PREVEND study, Groningen, Netherlands: 8141 participants without history of CVD, aged 28 to 75 years

Sources

Abbasi et al. Peroxiredoxin 4, a novel circulating biomarker for oxidative stress and the risk of incident cardiovascular disease and all-cause mortality. Journal of the American Heart Association. 2012;1:e002956.

Related markers: 3-Nitrotyrosine (3-NT) · 4-Hydroxynonenal (4-HNE) · 8-Hydroxy-2'-deoxyguanosine (8-OHdG) · Malondialdehyde (MDA) · Protein carbonyls · Total Plasma Thiols · Total thiol levels · Urinary 8-oxoGuo