Biomarkers · Hematology

Mean Platelet Volume (MPV)

Higher values go with lower risk of death. Not measured in our NHANES panel. The curve is drawn from the published study (source below).

MPV and risk of death

Published curve higher than the NHANES fitNHANES fit higher

Risk of death relative to the curve's reference value, drawn from the published study (source below).

Published risk of death0.79×highest vs lowest MPV quintile (Q5 mean MPV 10.0 fL) (95% CI 0.64–0.98) · Moli-sani study, Italy: adults randomly recruited from the general population (2005-2010)

MPV by age and sex

Each bar runs from the 5th to the 95th percentile, the darker part from the 25th to the 75th, and the tick is the median. Not a reference range or a target.

The percentiles as a table

Each row is one sex and age band: the values below which 5%, 25%, 50%, 75% and 95% of people fall (fL), from the survey named in the row. Not a reference range or a target.
Sex	Age	5th	25th	Median	75th	95th	n	Cycle / source
All	20-39	6.94	7.60	8.20	8.70	9.70	1,457	NHANES 2017-2018
All	40-59	7.00	7.50	8.10	8.80	9.90	1,584	NHANES 2017-2018
All	60+	7.00	7.70	8.20	8.80	9.90	1,940	NHANES 2017-2018
All	all	7.00	7.60	8.20	8.80	9.80	4,981	NHANES 2017-2018
Men	20-39	7.00	7.60	8.20	8.70	9.60	698	NHANES 2017-2018
Men	40-59	6.90	7.50	8.10	8.80	9.70	740	NHANES 2017-2018
Men	60+	7.00	7.60	8.10	8.60	9.60	981	NHANES 2017-2018
Men	all	6.90	7.60	8.10	8.73	9.60	2,419	NHANES 2017-2018
Women	20-39	6.90	7.70	8.20	8.80	9.75	759	NHANES 2017-2018
Women	40-59	7.10	7.60	8.20	8.80	9.94	844	NHANES 2017-2018
Women	60+	7.00	7.70	8.20	8.80	10.0	959	NHANES 2017-2018
Women	all	7.00	7.70	8.20	8.80	9.90	2,562	NHANES 2017-2018

What else moves this marker

They describe those study groups, not an individual, and an association is not a cause.

Diseases and conditions

Each row is one study: what it compared and the change it reported in this marker.
What	Effect on the marker	Comparison · population	Source
↑ Autoimmune thyroid disease · MPV in AITD patients vs healthy controls	SMD +0.256 (95% CI 0.013 to 0.5)	AITD patients vs healthy people · 19 articles; 3,824 AITD patients and 2,349 healthy controls	meta analysis · PMID 36618418
↑ Erectile dysfunction · MPV in men with ED vs controls	SMD +0.651 (95% CI 0.567 to 0.735)	ED subjects vs controls · 14 studies; 1,595 ED cases and 987 controls	meta analysis · PMID 30740770
↑ Preeclampsia · MPV in preeclamptic vs healthy pregnant women	+1.04 fL (95% CI 0.76 to 1.32)	Preeclampsia vs healthy pregnancy · Case-control studies; 7,905 women contributing to the pooled MD (50 studies, 14,614 women overall)	meta analysis · PMID 30177049
↑ Psoriasis · MPV in psoriasis patients vs healthy volunteers	SMD +0.503 (95% CI 0.242 to 0.765)	Psoriasis vs healthy controls · 10 studies of MPV; 1,331 psoriasis patients and 919 healthy volunteers overall	meta analysis · PMID 35213665
↑ Varicocele · MPV in varicocele patients vs healthy subjects	SMD +0.61 (95% CI 0.29 to 0.93)	Varicocele patients vs healthy subjects · 9 studies; 1,156 varicocele patients and 797 healthy subjects	meta analysis · PMID 33369777

Environmental and occupational exposures

Each row is one study: what it compared and the change it reported in this marker.
What	Effect on the marker	Comparison · population	Source
↑ Chronic high-altitude hypoxia (>=1 month) · MPV after chronic high-altitude exposure vs control group	SMD +1.55 (95% CI 0.6 to 2.49)	Chronic (>=1 month) high-altitude exposed vs controls · 32 studies of platelet indices and high-altitude exposure	meta analysis · PMID 35196458

Sources

Risk curve: Bonaccio 2017 (PMID 28357442): all-cause HR 0.79 (0.64-0.98) highest vs lowest MPV quintile (Q5 mean MPV 10.0 fL); protective form as reported. Scaled to US values (NHANES).
Bonaccio et al. Mean platelet volume is associated with lower risk of overall and non-vascular mortality in a general population. Results from the Moli-sani study. Thrombosis and haemostasis. 2017;117:1129-1140.

Map Mean Platelet Volume (MPV) against another biomarker.

Map MPV against another marker