Biomarkers · Oxidative Stress

Urinary F2-isoprostanes (8-iso-PGF2α)

No risk curve catalogued yet.

What studies found when this marker was changed

They describe what happened in those study groups, not a recommendation. See all catalogued interventions.

Measured changes in 8-iso-PGF2α, study by study

2 effects with a numeric size, each from one study arm: the dot is the reported change, the line its 95% interval where one was given. Study results in the groups studied, not predictions for a person.

Each row is one study: what was changed, the effect it reported on this marker, and the source.
Type	Intervention	Reported effect	Evidence	Source
supplement	Vitamin E 400 IU/day (all rac-alpha-tocopheryl acetate) vs placebo for 36 months in male current smokers (SELECT)	Urine 8-iso-PGF2alpha 21% lower with vitamin E than placebo at 36 months; n=312 smokers	RCT	Guertin KA, et al. Free Radic Biol Med. 2016;95:349-356.
supplement	Purified eicosapentaenoic acid 4 g/day vs olive oil for 6 weeks in treated-hypertensive type 2 diabetic adults	24 h urinary F2-isoprostanes 19% lower with EPA than olive oil after 6 weeks; 59 randomized	RCT	Mori TA, et al. Free Radic Biol Med. 2003;35(7):772-781.

Sources

See the catalogue entry in the research dashboard.