Biomarkers · Cardiac & Hemodynamics
QRS Duration
Lower values go with lower risk of death. Not measured in our NHANES panel. The curve is drawn from the published study (source below).
QRS Duration and risk of death
Published curve higher than the NHANES fitNHANES fit higher
Risk of death relative to the curve's reference value, drawn from the published study (source below).
What studies found when this marker was changed
They describe what happened in those study groups, not a recommendation. See all catalogued interventions.
Measured changes in QRS Duration, study by study
2 effects with a numeric size, each from one study arm: the dot is the reported change, the line its 95% interval where one was given. Green points move the marker the way lower risk of death lies; amber the other way. Study results in the groups studied, not predictions for a person.
| Type | Intervention | Reported effect | Evidence | Source |
|---|---|---|---|---|
| clinical | His-bundle or left bundle branch area pacing instead of conventional biventricular pacing for cardiac resynchronization in heart failure with reduced ejection fraction | Paced QRS duration 13.34 ms shorter (95% CI 2.36-24.32) with conduction system pacing than biventricular pacing; LVEF +2.06% | meta-analysis | Ferreira Felix I, Collini M, Fonseca R, et al. Conduction system pacing versus… |
| clinical | Left bundle branch pacing compared with biventricular pacing in the same patients during CRT implantation for heart failure with left bundle branch block | LBBP shortens QRS duration by a further 11 ms (95% CI 4-17) vs biventricular pacing, with greater QRS-area and dP/dtmax improvement | RCT | Liang Y, Wang J, Gong X, et al. Left Bundle Branch Pacing Versus Biventricular… |
Sources
- Risk curve: Aro 2011 (PMID 21841194): all-cause RR 1.48 (1.22-1.81) QRS duration >=110 ms vs <110 ms. Scaled to US values (NHANES).
- Aro et al. Intraventricular conduction delay in a standard 12-lead electrocardiogram as a predictor of mortality in the general population. Circulation. Arrhythmia and electrophysiology. 2011;4:704-10.
Map QRS Duration against another biomarker.
Related markers: Abdominal Aortic Calcification (AAC) · Ankle-Brachial Index (ABI) · Cardiac (Valvular/Annular) Calcification · Carotid Intima-Media Thickness (CIMT) · Carotid-Femoral Pulse Wave Velocity (PWV) · Copeptin · Coronary Artery Calcium Score (Agatston) · Corrected QT Interval (QTc)