PFLPhysiological Fitness Landscape

Biomarkers · Cardiac & Hemodynamics

Mean Arterial Pressure

The published study could not tell whether risk rises or falls: its 95% interval includes no change. In NHANES 1999–2018 with linked mortality to 2019, each standard deviation above average goes with 1% higher risk of death. No clear pattern in NHANES

Mean Arterial Pressure and risk of death

Published curve higher than the NHANES fitNHANES fit higher

Risk of death from our NHANES fit, relative to its reference value. The dotted vertical line marks the NHANES median.

Risk of death per SD (NHANES)1.01×95% CI 0.99–1.03 · 49,318 adults, 7,264 deaths
Published risk of death0.91×Q4 vs Q1 of MAP (lowest quartile as referent) (95% CI 0.37–2.24) · NHANES 1999-2006 young adults aged 18-40 years, mortality follow-up to 31 Dec 2015
Value of the measurement+0.008gain in concordance within age bands; rank 43 of 56 · all tests

Mean Arterial Pressure across cohorts

11.1HR per SD (95% CI)
NHANES · United States, 20–8449,318 people · 7,264 deaths1.01 0.99–1.03
HRS · United States, 50+24,148 people · 8,515 deaths1.03 1.01–1.06
Risk-of-death ratio per standard deviation, adjusted for age and sex, within each cohort. Cohorts differ in age range, assay, measurement protocol and follow-up, and one SD is a different amount in each, so the comparison is of direction and rough size per SD, not per unit. Vertical line: no association.

Mean Arterial Pressure by age and sex

Each bar runs from the 5th to the 95th percentile, the darker part from the 25th to the 75th, and the tick is the median. Not a reference range or a target.

The percentiles as a table
Each row is one sex and age band: the values below which 5%, 25%, 50%, 75% and 95% of people fall (mmHg), from the survey named in the row. Not a reference range or a target.
SexAge5th25thMedian75th95thnCycle / source
All20-3971.178.784.991.91051,449NHANES 2017-2018
All40-5975.585.191.399.61121,576NHANES 2017-2018
All60+72.782.990.098.91121,923NHANES 2017-2018
Allall72.482.088.796.91104,948NHANES 2017-2018
Men20-3973.281.688.095.0108704NHANES 2017-2018
Men40-5978.486.992.7101112744NHANES 2017-2018
Men60+73.383.891.198.9112980NHANES 2017-2018
Menall74.484.490.498.01112,428NHANES 2017-2018
Women20-3970.476.782.287.698.8745NHANES 2017-2018
Women40-5974.082.989.398.2112832NHANES 2017-2018
Women60+71.482.089.398.9111943NHANES 2017-2018
Womenall71.379.886.995.31102,520NHANES 2017-2018

What studies found when this marker was changed

They describe what happened in those study groups, not a recommendation. See all catalogued interventions.

Measured changes in Mean Arterial Pressure, study by study

4 effects with a numeric size, each from one study arm: the dot is the reported change, the line its 95% interval where one was given. Study results in the groups studied, not predictions for a person.

Each row is one study: what was changed, the effect it reported on this marker, and the source.
TypeInterventionReported effectEvidenceSource
exerciseAerobic exercise training; effect expressed per additional 30 minutes per week in adults with hypertensionMAP -1.37 mmHg (95% CI -1.80 to -0.93) per 30 min/week of aerobic exercisemeta-analysisJabbarzadeh Ganjeh B, Zeraattalab-Motlagh S, Jayedi A, et al. Hypertens Res…
exerciseIsometric resistance training vs sedentary or sham control in adults with hypertensionMAP -7.19 mmHg (95% CI -9.06 to -5.32) vs controlmeta-analysisBaffour-Awuah B, Pearson MJ, Dieberg G, et al. Curr Hypertens Rep. 2023.
exerciseWhole-body stretching 30 min/day, 5 days/week for 8 weeks in high-normal BP or stage 1 hypertensionSitting MAP fell from 108 to 103 mmHg after 8 weeks of stretching (walking group unchanged, 105 to 105)RCTKo J, Deprez D, Shaw K, et al. J Phys Act Health. 2021.
exerciseTwo consecutive yearly 16-week supervised high-intensity interval training programmes in adults with metabolic syndromeMAP fell from 101 to 94 mmHg over 2 years (control 98 to 99)RCTMorales-Palomo F, Ramirez-Jimenez M, Ortega JF, et al. Med Sci Sports Exerc…