Biomarkers · Nutritional

Serum trans-Lycopene

Higher values go with lower risk of death. Not measured in our NHANES panel. The curve is drawn from the published study (source below).

Serum trans-Lycopene and risk of death

Published curve higher than the NHANES fitNHANES fit higher

Risk of death relative to the curve's reference value, drawn from the published study (source below).

Published risk of death0.49×Q4 vs Q1 of serum trans-lycopene (95% CI 0.39–0.63) · NHANES 2003-2006 participants aged 20-85 years, USA, mortality linkage to 2015

Serum trans-Lycopene by age and sex

Each bar runs from the 5th to the 95th percentile, the darker part from the 25th to the 75th, and the tick is the median. Not a reference range or a target.

The percentiles as a table

Each row is one sex and age band: the values below which 5%, 25%, 50%, 75% and 95% of people fall (ug/dL), from the survey named in the row. Not a reference range or a target.
Sex	Age	5th	25th	Median	75th	95th	n	Cycle / source
All	20-39	9.22	15.6	21.6	27.3	39.8	1,372	NHANES 2017-2018
All	40-59	8.24	15.2	21.9	29.9	44.0	1,489	NHANES 2017-2018
All	60+	5.14	11.3	17.6	24.7	39.7	1,826	NHANES 2017-2018
All	all	7.24	14.1	20.4	27.8	41.1	4,687	NHANES 2017-2018
Men	20-39	10.2	16.8	22.2	29.3	42.1	658	NHANES 2017-2018
Men	40-59	8.19	16.1	23.1	31.6	43.5	699	NHANES 2017-2018
Men	60+	5.46	11.3	17.2	25.4	37.6	925	NHANES 2017-2018
Men	all	7.49	14.7	21.0	29.0	42.7	2,282	NHANES 2017-2018
Women	20-39	8.04	14.9	21.1	26.1	37.3	714	NHANES 2017-2018
Women	40-59	8.27	14.7	21.1	28.5	44.2	790	NHANES 2017-2018
Women	60+	4.74	11.3	17.9	24.1	40.5	901	NHANES 2017-2018
Women	all	6.72	13.7	19.9	26.5	39.8	2,405	NHANES 2017-2018

What studies found when this marker was changed

They describe what happened in those study groups, not a recommendation. See all catalogued interventions.

Measured changes in Serum trans-Lycopene, study by study

2 effects with a numeric size, each from one study arm: the dot is the reported change, the line its 95% interval where one was given. Green points move the marker the way lower risk of death lies; amber the other way. Study results in the groups studied, not predictions for a person.

Each row is one study: what was changed, the effect it reported on this marker, and the source.
Type	Intervention	Reported effect	Evidence	Source
diet	One meal per day of 470 g diced tomatoes cooked with 25 mL extra-virgin olive oil for 5 days after a low-lycopene run-in, in healthy adults	Plasma trans-lycopene rises 82% (P<0.001) after 5 days of tomatoes cooked with olive oil; no significant change when cooked without oil	RCT	Fielding JM, Rowley KG, Cooper P, O'Dea K. Increases in plasma lycopene…
diet	Daily consumption of 100% watermelon puree for 6 weeks in overweight/obese postmenopausal women	Fasting plasma trans-lycopene up 42% (P = .003) and cis-lycopene up 32% after 6 weeks of daily watermelon; sVCAM-1 -6%	RCT	Shanely RA, Zwetsloot JJ, Jurrissen TJ, et al. Daily watermelon consumption…

Sources

Risk curve: Zhang 2024 (PMID 36691936): all-cause HR 0.49 (0.39-0.63) Q4 vs Q1 of serum trans-lycopene. Scaled to US values (NHANES).
Zhang et al. Associations of different isomeric forms of serum lycopene with cardiovascular disease and all-cause mortality. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2024;94:108-119.

Map Serum trans-Lycopene against another biomarker.

Map Serum trans-Lycopene against another marker