What studies found when this marker was changed
They describe what happened in those study groups, not a recommendation. See all catalogued interventions.
Measured changes in Total Body Water Mass, study by study
1 effect with a numeric size, each from one study arm: the dot is the reported change, the line its 95% interval where one was given. Study results in the groups studied, not predictions for a person.
| Type | Intervention | Reported effect | Evidence | Source |
|---|---|---|---|---|
| pharmacologic | SGLT2 inhibitor therapy in patients with type 2 diabetes (25 RCTs, 2,286 participants) | Reduces total body water by 0.96 (95% CI -1.68 to -0.23) alongside -2.74 kg body weight and -0.80 kg lean mass | meta-analysis | Zhang S, et al. Frontiers in endocrinology. 2023. Effect of sodium-glucose… |
| pharmacologic | Empagliflozin 10 mg once daily vs placebo in patients with CKD (bioimpedance substudy, 660 participants) | Total body water lower vs placebo: extracellular water -0.49 L (95% CI -0.69 to -0.30) and intracellular water -0.30 L (95% CI -0.57 to -0.03); fluid overload -0.24 L | RCT | Mayne KJ, et al. Journal of the American Society of Nephrology : JASN. 2024… |
Sources
- See the catalogue entry in the research dashboard.
Related markers: Appendicular Lean Mass / Sarcopenia Index · Basal Metabolic Rate · Body Fat Percentage · Body Mass Index (BMI) · Body Weight · Calf Circumference · Fat Mass · Fat-Free Mass