PFLPhysiological Fitness Landscape

Biomarkers · Anthropometric

Basal Metabolic Rate

Both low and high values go with higher risk of death. No risk curve catalogued yet.

Published risk of death1.53×BMR >36.4 vs 31.3-33.9 kcal/m2/h (lowest-mortality range) (95% CI 1.19–1.96) · Baltimore Longitudinal Study of Aging (BLSA) participants (972 men), measured BMR, up to 40-year follow-up, USA

What studies found when this marker was changed

They describe what happened in those study groups, not a recommendation. See all catalogued interventions.

Measured changes in Basal Metabolic Rate, study by study

1 effect with a numeric size, each from one study arm: the dot is the reported change, the line its 95% interval where one was given. Study results in the groups studied, not predictions for a person.

Each row is one study: what was changed, the effect it reported on this marker, and the source.
TypeInterventionReported effectEvidenceSource
clinicalMetabolic bariatric surgery with or without a 26-week exercise programme in adults with severe obesity (POWER trial sub-study)Resting metabolic rate fell 356 kcal/day (SD 237) from baseline after bariatric surgery with 31.1 kg weight loss; n=47RCTFriedman L, et al. Clin Nutr. 2026;60:106623.
dietLosing the same total weight gradually rather than rapidly (slower rate of energy restriction) in adults with overweight/obesityGradual weight loss significantly preserved RMR by 407.48 kJ compared with rapid weight loss of similar magnitudemeta-analysisAshtary-Larky D, et al. Br J Nutr. 2020. Effects of gradual weight loss v…

What else moves this marker

They describe those study groups, not an individual, and an association is not a cause.

Diseases and conditions

Each row is one study: what it compared and the change it reported in this marker.
WhatEffect on the markerComparison · populationSource
↓ Narcolepsy · narcolepsy patients vs non-narcoleptic controlsSMD -0.17 (95% CI -0.52 to 0.18)narcolepsy patients vs controls · 48 metabolic-profiling studies of narcolepsy patients vs controlsmeta analysis · PMID 33740593